HSPs - Ambiguous Mediators of Immunity
Author | : Stuart Keith Calderwood |
Publisher | : Frontiers Media SA |
Total Pages | : 94 |
Release | : 2017-05-11 |
ISBN-10 | : 9782889451524 |
ISBN-13 | : 2889451526 |
Rating | : 4/5 (526 Downloads) |
Download or read book HSPs - Ambiguous Mediators of Immunity written by Stuart Keith Calderwood and published by Frontiers Media SA. This book was released on 2017-05-11 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat shock proteins (HSPs) were discovered as polypeptides induced by stress that can be found in all kingdoms of cellular organisms. Their functions were, a first enigmatic and these proteins were thus classified by molecular weight, as in—Hsp27, Hsp70, Hsp90, Hsp110. More recently, each of these size-classified molecules has attributed a role in protein folding, and they thus came to be known, as a class, as molecular chaperones. However, the they possess properties beyond chaperoning. Indeed, their discovery in the extracellular spaces suggested roles in regulation of the immune responses.