All of us have lurking in our DNA a most remarkable gene, which has a crucial job - it protects us from cancer. Known simply as p53, this gene constantly scans

Decades of research on the tumor suppressor p53 have revealed that it plays a significant role as a "guardian of the genome," protecting cells against genotoxic

This volume offers a comprehensive review of the functions of the p53 family. The contributors examine the normal roles of these transcription factors, their ev

This book provides the readers with an overview of research on p53, which has been shown to play a role in numerous crucial biological pathways in normal and ca

p53 has emerged as a key tumor suppressor and important target for novel cancer therapy. This book, written by world-leading p53 researchers including many of t